Rat Secondary Antibodies
Biolegend Spark PLUS B550TM Mouse IgG2a
Spark PLUS B550™ Mouse IgG2a, κ Isotype Ctrl [MOPC-173]; Isotype: Mouse IgG2a, κ; Apps: FC, ICFC; Size: 25 tests
Cayman Chemical Rat PRoxIsome ProlIfRatrA 96
An antifolate with anticancer activity an inhibitor of thymidylate synthase and dihydrofolate reductase (Kis 109 and 7 nM respectively) has increased potency for thymidylate kinase when polyglutaminated (Ki 1.3 nM) an inhibitor of glycinamide ribonucleotide formyltransferase (Kis 9300 and 65 nM for the non-glutaminated and polyglutaminated enzyme) and aminoimidazole carboxamide ribonucleotide formyltransferase (Kis 3600 and 265 nM for the non-glutaminated and polyglutaminated respectively) inhibits proliferation of CCRF-CEM cells but not 510-dideazatetrahydrofolate-resistant CR15 cells (IC50s 0.254 and 200 UM respectively) reduces tumor growth in A549 H1299 and PC-9 NSCLC mouse xenograft models but not in models using the same cell lines overexpressing thymidylate kinase
Carbosynth LLC. Rat monoclonal Rat anti Human IgG antibody
Immunoglobulin G (IgG) are antibody molecules. Each IgG is composed of four peptide chains - two heavy chains gamma and two light chains. Each IgG has two antigen binding sites. Other Immunoglobulins may be described in terms of polymers with the IgG structure considered the monomer.
Sigma Aldrich Fine Chemicals Biosciences MRS 1191 solid | 185222-90-6 | MFCD01867626 | 2MG
MRS 1191 solid | Mol Wt: 477.55 | 185222-90-6 | MFCD01867626 | 2MG
ABclonal Technology 700 Rabbit anti- CD162/PSGL-1
Involved in leukocyte adhesive activation Acts upstream of or within leukocyte tethering or rolling Predicted to be located in plasma membrane raft and uropod Predicted to be active in plasma membrane Is expressed in brain and thymus primordium Human ortholog(s) of this gene implicated in carotid artery disease Orthologous to human SELPLG (selectin P ligand)
ABclonal Technology APC/Cy7 anti-h/Mk CD19
This gene encodes a cell surface protein in the immunoglobulin superfamily expressed exclusively on B cell lymphocytes It serves as a marker for pre-B cells with expression decreasing as B cells differentiate into antibody-secreting plasma cells The protein contains two N-terminal Ig-like domains a non-Ig-like domain a transmembrane region and a large cytoplasmic domain It forms a complex with CD21 and CD81 lowering the threshold for antigen-triggered B cell activation which activates the PI3K signaling pathway and calcium release This protein is targeted by CAR T-cells for treating lymphoblastic leukemia Mutations are linked to common variable immunodeficiency 3 (CVID3) causing impaired B-cell differentiation hypogammaglobulinemia inability to respond to antigens and recurrent infections Alternative splicing produces multiple transcript variants encoding distinct isoforms
Azzota Corp Rat/Mouse Intubation 50g
Intubation Platform for Rat or Mouse Rats/Mice Operation Table 50g or less
ABclonal Technology 594 anti-Human CD162/PSGL-1
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P- E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes As such this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins This protein requires two post-translational modifications tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans for its high-affinity binding activity Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response Alternate splicing results in multiple transcript variants
ABclonal Technology 488 Rabbit anti- CD162/PSGL-1
Involved in leukocyte adhesive activation Acts upstream of or within leukocyte tethering or rolling Predicted to be located in plasma membrane raft and uropod Predicted to be active in plasma membrane Is expressed in brain and thymus primordium Human ortholog(s) of this gene implicated in carotid artery disease Orthologous to human SELPLG (selectin P ligand)